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Items: 3

1.

Systematic Bias in Genomic Classification Due to Contaminating Normal Tissue in Breast Tumor Samples

(Submitter supplied) Results: Normal tissue contamination caused misclassification of tumors in all predictors, but different breast cancer predictors showed different susceptibility to normal tissue bias. Sensitivity and negative predictive value (NPV) of the PAM50 assay was improved by accounting for normal tissue. Conclusions: Normal tissue sampled concurrently with tumor tissue is an important source of bias in genomic predictors. more...
Organism:
Homo sapiens
Type:
Expression profiling by array
4 related Platforms
118 Samples
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Series
Accession:
GSE22384
ID:
200022384
2.

UNC PerouLab 244K Custom Human Array version 5

(Submitter supplied) Agilent Technology (see manufacturer's website)
Organism:
Homo sapiens
11 Series
442 Samples
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Platform
Accession:
GPL8269
ID:
100008269
3.

071567A-244K

Organism:
Homo sapiens
Source name:
Human Reference B (channel 1) cancer-adjacent normal tissue (channel 2)
Platform:
GPL8269
Series:
GSE22384
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Sample
Accession:
GSM555502
ID:
300555502
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db=gds|term=GSM555502[Accession]|query=1|qty=2|blobid=MCID_6759c046df415c74f809d058|ismultiple=true|min_list=5|max_list=20|def_tree=20|def_list=|def_view=|url=/Taxonomy/backend/subset.cgi?|trace_url=/stat?
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