GSM555497[Accession] - GEO DataSets

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Items: 4

Select item 2000411191.

Molecular Characterization of Basal-like and Non-Basal-like Triple-Negative Breast Cancers

(Submitter supplied) Triple-negative (TN) and Basal-like (BL) breast cancer definitions have been used interchangeably to identify breast cancers that lack expression of the hormonal receptors (HR) and overexpression and/or amplification of HER2. However, both classifications when compared to each other, show substantial discordance rates. Here, we molecularly characterize TN tumors, and Basal-like tumors, and compare and contrast the results in terms of common patterns and distinct patterns for each. more...

Organism:: Homo sapiens

Type:: Expression profiling by array

Platform:: GPL8269
287 Samples

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Accession:: GSE41119

ID:: 200041119

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 2000223842.

Systematic Bias in Genomic Classification Due to Contaminating Normal Tissue in Breast Tumor Samples

(Submitter supplied) Results: Normal tissue contamination caused misclassification of tumors in all predictors, but different breast cancer predictors showed different susceptibility to normal tissue bias. Sensitivity and negative predictive value (NPV) of the PAM50 assay was improved by accounting for normal tissue. Conclusions: Normal tissue sampled concurrently with tumor tissue is an important source of bias in genomic predictors. more...