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Items: 3

1.

Epithelial TGFβ activation engages growth-factor signalling to circumvent cell death and drive intestinal tumorigenesis with aggressive features.

(Submitter supplied) The pro-tumourigenic role of epithelial TGFβ in colorectal cancer (CRC) has been controversial. Here we identify a cohort of aggressive ‘bad acting’ early-stage (T1) disseminating tumours characterised by high cell-intrinsic TGFβ signalling emanating from the epithelium, not stroma. To address its functional significance, we activated TGFβ signalling in the murine intestinal epithelium either alone or in concert with the common tumour suppressive and oncogenic mutations found in CRC, namely Apc and Kras. more...
Organism:
Mus musculus
Type:
Expression profiling by high throughput sequencing
Platform:
GPL19057
47 Samples
Download data: CSV
Series
Accession:
GSE182019
ID:
200182019

PubMed Full text in PMC Similar studies SRA Run Selector

2.

Illumina NextSeq 500 (Mus musculus)

Organism:
Mus musculus
10325 Series
296606 Samples
Download data
Platform
Accession:
GPL19057
ID:
100019057

3.

Apc Kras Alk5 Smad4 Rep 2

Organism:
Mus musculus
Source name:
Small Intestinal Tissue
Platform:
GPL19057
Series:
GSE182019
Download data
Sample
Accession:
GSM5516366
ID:
305516366

SRA Run Selector

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db=gds|term=GSM5516366[Accession]|query=1|qty=2|blobid=MCID_674aa4cfb594c03ae708449d|ismultiple=true|min_list=5|max_list=20|def_tree=20|def_list=|def_view=|url=/Taxonomy/backend/subset.cgi?|trace_url=/stat?
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