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Items: 3

1.

Ribosome collisions in bacteria promote ribosome rescue by triggering mRNA cleavage by SmrB

(Submitter supplied) Ribosome rescue pathways recycle stalled ribosomes and target problematic mRNAs and aborted proteins for degradation. In bacteria, it remains unclear how rescue pathways distinguish ribosomes stalled in the middle of a transcript from actively translating ribosomes. In a genetic screen in E. coli, we discovered a novel rescue factor that has endonuclease activity. SmrB cleaves mRNAs upstream of stalled ribosomes, allowing the ribosome rescue factor tmRNA (which acts on truncated mRNA) to rescue upstream ribosomes. more...
Organism:
Escherichia coli str. K-12 substr. MG1655
Type:
Expression profiling by high throughput sequencing
Platform:
GPL18956
4 Samples
Download data: TXT, WIG
Series
Accession:
GSE179691
ID:
200179691

PubMed Full text in PMC Similar studies SRA Run Selector

2.

Illumina HiSeq 2500 (Escherichia coli str. K-12 substr. MG1655)

Organism:
Escherichia coli str. K-12 substr. MG1655
30 Series
530 Samples
Download data
Platform
Accession:
GPL18956
ID:
100018956

3.

wild-type

Organism:
Escherichia coli str. K-12 substr. MG1655
Source name:
cell cultures
Platform:
GPL18956
Series:
GSE179691
Download data: WIG
Sample
Accession:
GSM5428381
ID:
305428381

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db=gds|term=GSM5428381[Accession]|query=1|qty=2|blobid=MCID_674f91072ced8a147a299454|ismultiple=true|min_list=5|max_list=20|def_tree=20|def_list=|def_view=|url=/Taxonomy/backend/subset.cgi?|trace_url=/stat?
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