GEO DataSets

(Submitter supplied) OVE26 (OVE) mice provide a useful model of advanced diabetic nephropathy (DN) with respect to albuminuria and pathologies. We showed that albuminuria, reduced GFR and interstitial fibrosis, which normally take 8-9 months to develop, are more advanced in uninephrectomized OVE mice within 10 weeks of surgery, at 4.5 months of age. The accelerated progression of renal damage, especially renal fibrosis in OVE-uni mice, was also identified at the gene expression level. more...

Organism:

Mus musculus

Type:

Expression profiling by array

Dataset:

GDS3990

Platform:

GPL1261

4 Samples

Download data: CEL

Analysis of kidney from 4.5 month-old OVE26 (OVE) diabetic nephropathy (DN) females following uninephrectomy of the left kidney 10 weeks prior. Uninephrectomy dramatically exacerbated DN in OVE mice. Results provide insight into the molecular basis of diabetic pathology over a short period of time.

Organism:

Mus musculus

Type:

Expression profiling by array, count, 2 disease state, 2 genotype/variation, 2 protocol sets

Platform:

GPL1261

Series:

GSE21448

4 Samples

Download data: CEL

(Submitter supplied) Affymetrix submissions are typically submitted to GEO using the GEOarchive method described at http://www.ncbi.nlm.nih.gov/projects/geo/info/geo_affy.html June 03, 2009: annotation table updated with netaffx build 28 June 07, 2012: annotation table updated with netaffx build 32 June 23, 2016: annotation table updated with netaffx build 35 Protocol: see manufacturer's web site All probe sets represented on the GeneChip Mouse Expression Set 430 are included on the GeneChip Mouse Genome 430 2.0 Array. more...

Organism:

Mus musculus

601 DataSets

4547 Series

40 Related Platforms

58950 Samples

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