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Items: 4

1.

Molecular and Functional Characterization of the role of RNA silencing components in Cryptococcus neoformans

(Submitter supplied) The RNA interference (RNAi) mediated by homology-dependent degradation of the target mRNA with small RNA molecules plays a key role in controlling transcription and translation processes in a number of eukaryotic organisms. The RNAi machinery is also evolutionarily conserved in a wide variety of fungal species, including pathogenic fungi. To elucidate the physiological functions of the RNAi pathway in Cryptococcus neoformans that causes fungal meningitis, here we performed genetic analyses for genes encoding Argonaute (AGO1 and AGO2), RdRP (RDP1), and Dicers (DCR1 and DCR2) in both serotype A and D C. more...
Organism:
Cryptococcus neoformans var. neoformans JEC21; Cryptococcus neoformans var. grubii H99
Type:
Expression profiling by array
Platform:
GPL8638
22 Samples
Download data: GPR
Series
Accession:
GSE21178
ID:
200021178
2.

Molecular and Functional Characterization of the role of RNA silencing components in Cryptococcus neoformans [RNAi_Serotype A]

(Submitter supplied) The RNA interference (RNAi) mediated by homology-dependent degradation of the target mRNA with small RNA molecules plays a key role in controlling transcription and translation processes in a number of eukaryotic organisms. The RNAi machinery is also evolutionarily conserved in a wide variety of fungal species, including pathogenic fungi. To elucidate the physiological functions of the RNAi pathway in Cryptococcus neoformans that causes fungal meningitis, here we performed genetic analyses for genes encoding Argonaute (AGO1 and AGO2), RdRP (RDP1), and Dicers (DCR1 and DCR2) in both serotype A and D C. more...
Organism:
Cryptococcus neoformans var. neoformans JEC21; Cryptococcus neoformans var. grubii H99
Type:
Expression profiling by array
Platform:
GPL8638
16 Samples
Download data: GPR
Series
Accession:
GSE21176
ID:
200021176
3.

Duke Cryptococcus neoformans serotype D (JEC21) 8K

(Submitter supplied) 70-mer oligonucleotides.
Organism:
Cryptococcus neoformans var. neoformans JEC21
15 Series
267 Samples
Download data
Platform
Accession:
GPL8638
ID:
100008638
4.

H99 YPD 2nd

Organism:
Cryptococcus neoformans var. grubii H99
Source name:
H99 YPD 2nd (channel 1) pooled total RNA from all strain all time point all stress (channel 2)
Platform:
GPL8638
Series:
GSE21176 GSE21178
Download data: GPR
Sample
Accession:
GSM530036
ID:
300530036
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