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Items: 3

1.

STING mediates immune responses in a unicellular choanoflagellate

(Submitter supplied) To reconstruct the ancestry of animal innate immunity, we have developed the choanoflagellate Monosiga brevicollis, one of the closest living relatives of animals, as a model for studying mechanisms underlying pathogen recognition and immune response. We found that M. brevicollis is killed by exposure to Pseudomonas aeruginosa bacteria and selectively avoids ingesting them. Moreover, M. brevicollis expresses STING, which, in animals, activates innate immune pathways in response to cyclic dinucleotides during pathogen sensing. more...
Organism:
Monosiga brevicollis
Type:
Expression profiling by high throughput sequencing
Platforms:
GPL30126 GPL30125
24 Samples
Download data: TAB
Series
Accession:
GSE174340
ID:
200174340
2.

Illumina NextSeq 500 (Monosiga brevicollis)

Organism:
Monosiga brevicollis
1 Series
20 Samples
Download data
Platform
Accession:
GPL30125
ID:
100030125
3.

Control3

Organism:
Monosiga brevicollis
Source name:
choanoflagellate cells
Platform:
GPL30125
Series:
GSE174340
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Sample
Accession:
GSM5292355
ID:
305292355
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db=gds|term=GSM5292355[Accession]|query=1|qty=2|blobid=MCID_6759928a123afd30a72f93d0|ismultiple=true|min_list=5|max_list=20|def_tree=20|def_list=|def_view=|url=/Taxonomy/backend/subset.cgi?|trace_url=/stat?
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