GSM507453[Accession] - GEO DataSets

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Items: 3

Select item 2000202481.

Genomic analysis of microRNA time-course expression in liver of mice treated with genotoxic carcinogen N-ethyl-N-nitrosourea

(Submitter supplied) Dysregulated expression of microRNA (miRNA) has been extensively detected in human cancer tissues and has shown promise in defining tumor status. It, however, is little known whether and when expression of miRNAs can be changed in normal tissues after carcinogen exposure. To explore possible time-course changes of miRNA expression induced by carcinogens, we treated mice with one dose of 120 mg/kg body weight model genotoxic carcinogen N-ethyl-N-nitrosourea (ENU) and vehicle control. more...

Organism:: Mus musculus

Type:: Other

Platform:: GPL10006
35 Samples

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Accession:: GSE20248

ID:: 200020248

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 1000100062.

RT2 miRNA Mouse Genome PCR Array

(Submitter supplied) MicroRNA (miRNA), first discovered in C. elegans in early 1990s, are a class of naturally occurring small RNA molecules, generally 17 to 30 nucleotides long, processed from much larger stem-loop structures (pri-miRNA and pre-miRNA). Mature miRNA is recognized by and guides the RNA-Induced Silencing Complex (RISC) to specific messenger RNA transcript sequences, causing either translation repression or mRNA degradation. more...