GSM470431[Accession] - GEO DataSets

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Items: 3

Select item 2000190151.

The Sen1 Helicase Prevents Spurious Transcription by Controlling Genome-Wide Transcription Termination by RNAPII

(Submitter supplied) RNA Polymerase II (RNAPII) termination for transcripts containing a polyadenylation signal (PAS) is thought to differ mechanistically from termination for PAS-independent RNAPII transcripts such as sn(o)RNAs. In a screen for factors required for PAS-dependent termination, we identified Sen1, a putative helicase known primarily for its role in PAS-independent termination. We show that Sen1 is required for termination on hundreds of protein-coding genes and suppresses cryptic transcription from nucleosome-free regions on a genomic scale. more...

Organism:: Saccharomyces cerevisiae

Type:: Genome binding/occupancy profiling by genome tiling array

Platform:: GPL3737
10 Samples

Download data: GPR, TIFF

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Accession:: GSE19015

ID:: 200019015

Analyze with GEO2R

Select item 1000037372.

Agilent-012713 Yeast Whole Genome ChIP-on-chip Microarray (G4486A)

(Submitter supplied) The Yeast Whole Genome ChIP-on-chip microarray is a high-resolution, high performance 60-mer oligonucleotide that allows the location analysis of DNA binding proteins over 85% (the non-repetitive portion) of 12MB of the yeast genome on a single chip. This chip offers genome-wide coverage and consists of 41,441 oligos (60mer); 14,256 from intergenic pathway, 27,175 from ORF pathway with an average prob spacing of approximately every 266 bp. more...