GSM4696254[Accession] - GEO DataSets

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Items: 4

Select item 2001551441.

FACT is recruited to the +1 nucleosome of transcribed genes and spreads in a Chd1-dependent manner

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:: Saccharomyces cerevisiae

Type:: Genome binding/occupancy profiling by array; Genome binding/occupancy profiling by high throughput sequencing

Platforms:: GPL21656 GPL18340 GPL27812
256 Samples

Download data: BW, GPR

Series

Accession:: GSE155144

ID:: 200155144

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 2001551432.

FACT is recruited to the +1 nucleosome of transcribed genes and spreads in a Chd1-dependent manner [MNase-ChIP-Seq]

(Submitter supplied) The histone chaperone FACT occupies transcribed regions where it plays prominent roles in maintaining chromatin integrity and preserving epigenetic information. How it is targeted to transcribed regions, however, remains unclear. Proposed models for how FACT finds its way to transcriptionally active chromatin include docking on the RNA polymerase II (RNAPII) C-terminal domain (CTD), recruitment by elongation factors, recognition of modified histone tails and binding partially disassembled nucleosomes. more...