GSM4214724[Accession] - GEO DataSets

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Items: 4

Select item 2001418531.

Genetic Variations in Type 1 Diabetes Reconfigure the 3D Chromatin Organization of T Cells

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:: Mus musculus

Type:: Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing

Platforms:: GPL19057 GPL21626
52 Samples

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Series

Accession:: GSE141853

ID:: 200141853

PubMed Full text in PMC Similar studies

Select item 2001418522.

Genetic Variations in Type 1 Diabetes Reconfigure the 3D Chromatin Organization of T Cells [RNA-seq]

(Submitter supplied) Despite overwhelming evidence supporting the role of genetics in susceptibility tocomplex diseases, such as autoimmune disorders, a fundamental unresolved questionis whether large numbers of sequence variants with small effect sizes can alter thespatial genome organization. Here, we provide the first report on the reconfiguration ofthe 3D genome due to nucleotide differences associated with type 1 diabetes, anautoimmune disorder. more...