GEO DataSets

(Submitter supplied) In vertebrate muscle, loss of Dysferlin results in the activation of compensatory muscle gene expression, even at pre-pathological stages. We hypothesized that if C. elegans fer-1 is also expressed in muscle, then fer-1 mutant worms might also exhibit compensatory muscle gene expression. To test this hypothesis, we used Affymetrix microarrays to profile gene expression from synchronized wild type and fer-1 mutant adults. more...

Organism:

Caenorhabditis elegans

Type:

Expression profiling by array

Dataset:

GDS3579

Platform:

GPL200

12 Samples

Download data: CEL

Analysis of fer-1 loss of function C. elegans mutants. The fer-1 gene encodes a homolog for the human Dysferlin gene. Mutations in the human Dysferlin gene results in Limb Girdle Muscular Dystrophy 2B (LGMD2B). Results provide insight into the molecular pathogenesis of LGMD2B.

Organism:

Caenorhabditis elegans

Type:

Expression profiling by array, transformed count, 3 genotype/variation sets

Platform:

GPL200

Series:

GSE16753

12 Samples

Download data: CEL

(Submitter supplied) Affymetrix submissions are typically submitted to GEO using the GEOarchive method described at http://www.ncbi.nlm.nih.gov/projects/geo/info/geo_affy.html Has 22625 entries and was indexed 30-Apr-2002. Sequence information used for the design of the C. elegans array was downloaded from the Sanger Center database on December 05, 2000 and from GenBank release 121. All sequences were functionally reannotated by Affymetrix for improved descriptions. more...

Organism:

Caenorhabditis elegans

29 DataSets

181 Series

5 Related Platforms

2426 Samples

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