GEO DataSets

(Submitter supplied) Autologous chondrocyte transplantation (ACT) is a routine technique to regenerate focal cartilage lesions. However, patients with osteoarthritis (OA) are lacking an appropriate long-lasting treatment alternative, partly since it is not known if chondrocytes from OA patients have the same chondrogenic differentiation potential as chondrocytes from donors not affected by OA. Articular chondrocytes from patients with OA undergoing total knee replacement (Mankin Score >3, Ahlbäck Score >2) and from patients undergoing ACT, here referred to as normal donors (ND), were isolated applying protocols used for ACT. more...

Organism:

Homo sapiens

Type:

Expression profiling by array

Dataset:

GDS3758

Platform:

GPL570

12 Samples

Download data: CEL, EXP

Analysis of monolayer cultures and Hyaff-11 scaffold cultures of chondrocytes from 3 donors suffering from osteoarthritis (OA). Results provide insight into the differentiation process of OA chondrocytes and their possible use in matrix-associated autologous chondrocyte transplantation (ACT).

Organism:

Homo sapiens

Type:

Expression profiling by array, count, 2 disease state, 2 growth protocol sets

Platform:

GPL570

Series:

GSE16464

12 Samples

Download data: CEL, EXP

(Submitter supplied) Affymetrix submissions are typically submitted to GEO using the GEOarchive method described at http://www.ncbi.nlm.nih.gov/projects/geo/info/geo_affy.html June 03, 2009: annotation table updated with netaffx build 28 June 06, 2012: annotation table updated with netaffx build 32 June 23, 2016: annotation table updated with netaffx build 35 Protocol: see manufacturer's web site Complete coverage of the Human Genome U133 Set plus 6,500 additional genes for analysis of over 47,000 transcripts All probe sets represented on the GeneChip Human Genome U133 Set are identically replicated on the GeneChip Human Genome U133 Plus 2.0 Array. more...

Organism:

Homo sapiens

602 DataSets

5670 Series

61 Related Platforms

175576 Samples

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