GSM413801[Accession] - GEO DataSets

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Items: 4

Select item 2000164611.

Gene expression profile in CD4+ and CD8+ T cells from identical twins discordant for Multiple sclerosis

(Submitter supplied) To gain insight into the etiopathogenesis of Multiple sclerosis (MS) we investigated gene expression changes in CD4+ and CD8+ T lymphocytes from monozygotic twins (MZ) discordant for relapsing remitting MS. We studied 4 monozygotic twin pairs discordant for disease, with the affected co-twin free of disease modifying therapies (F/M = 3/1, mean age 36.25±3.9). Following leukapheresis, CD4+ and CD8+ T cells were separated and studied by Affymetrix GeneChip®

Organism:: Homo sapiens

Type:: Expression profiling by array

Dataset:: GDS4150
Platform:: GPL570
16 Samples

Download data: CEL

Series

Accession:: GSE16461

ID:: 200016461

Select item 41502.

Identical twins discordant for Multiple sclerosis: CD4+ and CD8+ T cells

Analysis of CD4+ and CD8+ T lymphocytes sorted from PBMCs from 4 monozygotic twin pairs discordant for relapsing remitting Multiple sclerosis (RRMS). The affected twin was free of disease-modifying therapies. Results provide insight into molecular mechanisms underlying the etiopathogenesis of RRMS.

Organism:: Homo sapiens

Type:: Expression profiling by array, count, 2 cell type, 2 disease state, 4 individual sets

Platform:: GPL570
Series:: GSE16461
16 Samples

Download data: CEL

DataSet

Accession:: GDS4150

ID:: 4150

Select item 1000005703.

[HG-U133_Plus_2] Affymetrix Human Genome U133 Plus 2.0 Array

(Submitter supplied) Affymetrix submissions are typically submitted to GEO using the GEOarchive method described at http://www.ncbi.nlm.nih.gov/projects/geo/info/geo_affy.html June 03, 2009: annotation table updated with netaffx build 28 June 06, 2012: annotation table updated with netaffx build 32 June 23, 2016: annotation table updated with netaffx build 35 Protocol: see manufacturer's web site Complete coverage of the Human Genome U133 Set plus 6,500 additional genes for analysis of over 47,000 transcripts All probe sets represented on the GeneChip Human Genome U133 Set are identically replicated on the GeneChip Human Genome U133 Plus 2.0 Array. more...