GSM4105754[Accession] - GEO DataSets

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Items: 3

Select item 2001383421.

Epigenetic pattern after EZH1,2 inhibition in lymohoma cells

(Submitter supplied) Although global H3K27me3 reprogramming is a hallmark of cancer, no effective therapeutic strategy for H3K27me3-high malignancies harboring EZH2WT/WT has yet been established. We explored epigenome and transcriptome in EZH2WT/WT aggressive lymphomas, and found that mutual interference and compensatory function of co-expressed EZH1 and EZH2 rearrange their own genome-wide distribution, thereby establishing restricted chromatin and gene expression signatures. more...

Organism:: Homo sapiens

Type:: Genome binding/occupancy profiling by genome tiling array

Platform:: GPL19784
117 Samples

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Accession:: GSE138342

ID:: 200138342

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Select item 1000197842.

Agilent-027954 SurePrint G3 Human Promoter Microarray 2x400K [Probe Name version]

(Submitter supplied) SurePrint G3 Human Promoter Microarray 2x400K Arrays of this design have barcodes that begin with 16027954 or 2527954. Orientation: Features are numbered numbered Left-to-Right, Top-to-Bottom as scanned by an Agilent scanner (barcode on the left, DNA on the back surface, scanned through the glass), matching the FeatureNum output from Agilent's Feature Extraction software. The ID column represents the Agilent Probe Name. more...