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Items: 3

1.

DOT1L-controlled cell-fate determination and transcription elongation are independent of H3K79 methylation

(Submitter supplied) Actively transcribed genes in mammals are decorated by H3K79 methylation, which is correlated with transcription levels and is catalyzed by the histone methyltransferase DOT1L. DOT1L is required for mammalian development, and the inhibition of its catalytic activity has been extensively studied for cancer therapy; however, the mechanisms underlying DOT1L’s functions in normal development and cancer pathogenesis remain elusive. more...
Organism:
Mus musculus
Type:
Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing; Other
Platform:
GPL19057
66 Samples
Download data: BW
Series
Accession:
GSE134083
ID:
200134083

PubMed Full text in PMC Similar studies SRA Run Selector

2.

Illumina NextSeq 500 (Mus musculus)

Organism:
Mus musculus
10325 Series
296606 Samples
Download data
Platform
Accession:
GPL19057
ID:
100019057

3.

DOT1LKO2_ESC_Pol2

Organism:
Mus musculus
Source name:
embryonic stem cell
Platform:
GPL19057
Series:
GSE134083
Download data: BW
Sample
Accession:
GSM3936477
ID:
303936477

SRA Run Selector

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db=gds|term=GSM3936477[Accession]|query=1|qty=2|blobid=MCID_6749c1644e6f392e264be32b|ismultiple=true|min_list=5|max_list=20|def_tree=20|def_list=|def_view=|url=/Taxonomy/backend/subset.cgi?|trace_url=/stat?
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