GEO DataSets

(Submitter supplied) Although a number of animal model studies have addressed changes in gene expression in the parenchyma and their relationship to emphysema, much less is known about the pathogenesis of cigarette smoke-induced small airway remodeling. In this study, we exposed rat tracheal explants to whole smoke for 15 minutes, and then cultured the explants in air. The airway transcriptome was evaluated using RAE 230_2 GeneChips. more...

Organism:

Rattus norvegicus

Type:

Expression profiling by array

Dataset:

GDS3746

Platform:

GPL1355

47 Samples

Download data: CEL

Analysis of tracheal explants at 2hrs and 24hrs following brief exposure to whole smoke. Some of the explants were pretreated with dexamethasone prior to smoke exposure. Results provide insight into the molecular mechanisms underlying pathogenesis of cigarette smoke-induced small airway remodeling.

Organism:

Rattus norvegicus

Type:

Expression profiling by array, count, 4 stress, 2 time sets

Platform:

GPL1355

Series:

GSE15563

47 Samples

Download data: CEL

(Submitter supplied) Affymetrix submissions are typically submitted to GEO using the GEOarchive method described at http://www.ncbi.nlm.nih.gov/projects/geo/info/geo_affy.html June 03, 2009: annotation table updated with netaffx build 28 June 07, 2012: annotation table updated with netaffx build 32 June 27, 2016: annotation table updated with netaffx build 35 Protocol: see manufacturer's web site The GeneChip Rat Genome 230 2.0 Array is a powerful tool for toxicology, neurobiology, and other applications using rat as a model organism. more...

Organism:

Rattus norvegicus

107 DataSets

750 Series

13 Related Platforms

23059 Samples

Download data