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Items: 5

1.

Peripheral blood mononuclear, DU145, and HCT116 cells treated with a CDK inhibitor

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.
Organism:
Homo sapiens
Type:
Expression profiling by array
Platform:
GPL570
156 Samples
Download data: CEL
Series
Accession:
GSE15396
ID:
200015396

PubMed Similar studies Analyze with GEO2R

2.

DU145 tumor cells treated with a CDK inhibitor

(Submitter supplied) A genomics-based approach to identify pharmacodynamic biomarkers was used for a CDK (cyclin-dependent kinase) inhibitory drug. R547 is a potent CDK inhibitor with a potent anti-proliferative effect at pharmacologically relevant doses, and is currently in Phase I clinical trials. Utilizing preclinical data derived from microarray experiments, we identified pharmacodynamic biomarkers to test in blood samples from patients in clinical trials. more...
Organism:
Homo sapiens
Type:
Expression profiling by array
Dataset:
GDS5267
Platform:
GPL570
45 Samples
Download data: CEL
Series
Accession:
GSE15392
ID:
200015392

PubMed Similar studies Analyze with GEO2R

3.
Full record GDS5267

Cyclin-dependent kinase inhibitor R547 effect on prostate cancer cell line: dose response and time course

Analysis of DU145 prostate cancer cells treated with the CDK inhibitor R547 at 3 doses for up to 24 hours. R547 exerts an antiproliferative effect on various cell lines. Results compared with those from PBMCs (GDS5266) and HCT116 cells (GDS5268) to identify pharmacodynamic biomarkers for R547.
Organism:
Homo sapiens
Type:
Expression profiling by array, count, 3 agent, 4 dose, 4 time sets
Platform:
GPL570
Series:
GSE15392
45 Samples
Download data: CEL
DataSet
Accession:
GDS5267
ID:
5267

PubMed Similar studies GEO Profiles Analyze DataSet

4.

[HG-U133_Plus_2] Affymetrix Human Genome U133 Plus 2.0 Array

(Submitter supplied) Affymetrix submissions are typically submitted to GEO using the GEOarchive method described at http://www.ncbi.nlm.nih.gov/projects/geo/info/geo_affy.html June 03, 2009: annotation table updated with netaffx build 28 June 06, 2012: annotation table updated with netaffx build 32 June 23, 2016: annotation table updated with netaffx build 35 Protocol: see manufacturer's web site Complete coverage of the Human Genome U133 Set plus 6,500 additional genes for analysis of over 47,000 transcripts All probe sets represented on the GeneChip Human Genome U133 Set are identically replicated on the GeneChip Human Genome U133 Plus 2.0 Array. more...
Organism:
Homo sapiens
602 DataSets
5670 Series
61 Related Platforms
175576 Samples
Download data
Platform
Accession:
GPL570
ID:
100000570

5.

DU145 cells treated with vehicle (DMSO) for 6 hours, replicate d

Organism:
Homo sapiens
Source name:
DU145 cells treated with vehicle (DMSO) for 6 hours, replicate d
Platform:
GPL570
Series:
GSE15392 GSE15396
Dataset:
GDS5267
Download data: CEL
Sample
Accession:
GSM386331
ID:
300386331

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