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Items: 4

1.

Topoisomerase II-induced Chromosome Breakage and Translocation Is Determined by Chromosome Architecture and Transcriptional Activity [END-seq]

(Submitter supplied) Topoisomerase II (TOP2) relieves torsional stress during transcription, DNA replication and chromosome segregation, by forming transient cleavage complex intermediates (TOP2ccs) that contain TOP2-linked DNA breaks. While TOP2ccs are normally reversible they can be ‘trapped’ by chemotherapeutic drugs such as etoposide, and subsequently converted into irreversible TOP2-linked DSBs that threaten genome stability. more...
Organism:
Homo sapiens; Mus musculus
Type:
Other
Platforms:
GPL21626 GPL21697
48 Samples
Download data: BW
Series
Accession:
GSE129524
ID:
200129524

PubMed Full text in PMC Similar studies SRA Run Selector

2.

Topoisomerase II-induced Chromosome Breakage and Translocation Is Determined by Chromosome Architecture and Transcriptional Activity

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.
Organism:
Mus musculus; Homo sapiens
Type:
Other; Genome binding/occupancy profiling by high throughput sequencing; Expression profiling by high throughput sequencing
Platforms:
GPL16417 GPL21697 GPL21626
73 Samples
Download data: BW, TXT
Series
Accession:
GSE129529
ID:
200129529

PubMed Full text in PMC Similar studies

3.

NextSeq 550 (Mus musculus)

Organism:
Mus musculus
1398 Series
59735 Samples
Download data
Platform
Accession:
GPL21626
ID:
100021626

4.

END_seq_ExoT_PB_LIG4_7_5h_TIME_COURSE

Organism:
Mus musculus
Source name:
Abelson-transformed pre-B cell
Platform:
GPL21626
Series:
GSE129524 GSE129529
Download data: BW
Sample
Accession:
GSM3714881
ID:
303714881

SRA Run Selector

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db=gds|term=GSM3714881[Accession]|query=1|qty=3|blobid=MCID_6748cda843705129cf4937ba|ismultiple=true|min_list=5|max_list=20|def_tree=20|def_list=|def_view=|url=/Taxonomy/backend/subset.cgi?|trace_url=/stat?
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