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Items: 4

1.

Analysis of the retinal gene expression after hypoxic preconditioning identifies candidate genes for neuroprotection

(Submitter supplied) Neuroprotective therapies for retinal degeneration may be used to rescue retinal cells and preserve vision. Hypoxic preconditioning stabilizes the transcription factor HIF-1α in the retina and strongly protects photoreceptors in an animal model of light-induced retinal degeneration. Our data suggest that neuroprotection after hypoxic preconditioning of the retina is the result of the differential expression of a multitude of genes which may act in concert to protect visual cells against a toxic insult. more...
Organism:
Mus musculus
Type:
Expression profiling by array
Dataset:
GDS3521
Platform:
GPL1261
24 Samples
Download data: CEL
Series
Accession:
GSE14366
ID:
200014366
2.
Full record GDS3521

Retina response to hypoxia and subsequent reoxygenation: time course

Analysis of retinas subjected to hypoxia for 6 hours and subsequent reoxygenation for up to 16 hours. Hypoxic preconditioning protects photoreceptors from light damage in animal model. Results provide insight into the molecular basis of this protective effect.
Organism:
Mus musculus
Type:
Expression profiling by array, transformed count, 2 protocol, 4 time sets
Platform:
GPL1261
Series:
GSE14366
24 Samples
Download data: CEL
3.

[Mouse430_2] Affymetrix Mouse Genome 430 2.0 Array

(Submitter supplied) Affymetrix submissions are typically submitted to GEO using the GEOarchive method described at http://www.ncbi.nlm.nih.gov/projects/geo/info/geo_affy.html June 03, 2009: annotation table updated with netaffx build 28 June 07, 2012: annotation table updated with netaffx build 32 June 23, 2016: annotation table updated with netaffx build 35 Protocol: see manufacturer's web site All probe sets represented on the GeneChip Mouse Expression Set 430 are included on the GeneChip Mouse Genome 430 2.0 Array. more...
Organism:
Mus musculus
601 DataSets
4547 Series
40 Related Platforms
58950 Samples
Download data
Platform
Accession:
GPL1261
ID:
100001261
4.

retina_hypox_4h_1

Organism:
Mus musculus
Source name:
retina after 4 h hypoxic treatment
Platform:
GPL1261
Series:
GSE14366
Dataset:
GDS3521
Download data: CEL
Sample
Accession:
GSM359266
ID:
300359266
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