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Items: 3

1.

Checkpoint blockade immunotherapy induces dynamic changes in PD-1-CD8+ tumor-infiltrating T cells

(Submitter supplied) An improved understanding of the anti-tumor CD8+ T cell response after checkpoint blockade would enable more informed and effective therapeutic strategies. Here we examined the dynamics of the effector response of CD8+ tumor-infiltrating lymphocytes (TILs) after checkpoint blockade therapy. Bulk and single-cell RNA profiles of CD8+ TILs after combined Tim-3+PD-1 blockade in preclinical models revealed significant changes in the transcriptional profile of PD-1? TILs. more...
Organism:
Mus musculus
Type:
Expression profiling by high throughput sequencing
Platforms:
GPL19057 GPL17021
28 Samples
Download data: TXT
Series
Accession:
GSE122969
ID:
200122969

PubMed Full text in PMC Similar studies SRA Run Selector

2.

Illumina HiSeq 2500 (Mus musculus)

Organism:
Mus musculus
11140 Series
299753 Samples
Download data
Platform
Accession:
GPL17021
ID:
100017021

3.

Tim-3-PD-1- CD8+_antiTim3+antiPD1 rep2

Organism:
Mus musculus
Source name:
Tumor MC38-OVA
Platform:
GPL17021
Series:
GSE122969
Download data
Sample
Accession:
GSM3530486
ID:
303530486

SRA Run Selector

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db=gds|term=GSM3530486[Accession]|query=1|qty=2|blobid=MCID_674fa52768e51b28f585530d|ismultiple=true|min_list=5|max_list=20|def_tree=20|def_list=|def_view=|url=/Taxonomy/backend/subset.cgi?|trace_url=/stat?
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