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Items: 3

1.

Jarid2 Functions as a Tumor Suppressor in Myeloid Neoplasms by Repressing Self-Renewal in Hematopoietic Progenitor Cells

(Submitter supplied) How specific genetic lesions contribute to transformation of non-malignant myeloproliferative neoplasms (MPN) and myelodysplastic syndromes (MDS) to secondary acute myeloid leukemia (sAML) are poorly understood. The JARID2 gene is lost by chromosomal deletions in a proportion of MPN/MDS patients who progress to sAML. In this study, genetic mouse models and patient-derived xenografts (PDX) demonstrated that Jarid2 acts as a tumor suppressor in chronic myeloid disorders. more...
Organism:
Mus musculus
Type:
Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing
Platform:
GPL21493
32 Samples
Download data: BW, TXT
Series
Accession:
GSE120595
ID:
200120595

PubMed Full text in PMC Similar studies SRA Run Selector

2.

Illumina HiSeq 3000 (Mus musculus)

Organism:
Mus musculus
1139 Series
42555 Samples
Download data
Platform
Accession:
GPL21493
ID:
100021493

3.

Vav-Jarid2-KO MPP H3K27me3-ChIP 2

Organism:
Mus musculus
Source name:
Multipotent Progenitor Cells (MPPs)
Platform:
GPL21493
Series:
GSE120595
Download data: BW
Sample
Accession:
GSM3405449
ID:
303405449

SRA Run Selector

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db=gds|term=GSM3405449[Accession]|query=1|qty=2|blobid=MCID_67596802c087e367329fcac5|ismultiple=true|min_list=5|max_list=20|def_tree=20|def_list=|def_view=|url=/Taxonomy/backend/subset.cgi?|trace_url=/stat?
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