GSM338866[Accession] - GEO DataSets

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Items: 4

Select item 2000134281.

Gene Expression Profiling of Rat Hippocampus Following Exposure to the Acetylcholinesterase Inhibitor Soman

(Submitter supplied) Soman (O-Pinacolyl methylphosphonofluoridate) is a potent neurotoxicant. Acute exposure to soman causes profound inhibition of the critical enzyme acetylcholinesterase, resulting in excessive levels of the neurotransmitter acetylcholine. Excessive acetylcholine levels cause convulsions, seizures, and respiratory distress. The initial cholinergic crisis can be overcome by rapid anti-cholinergic therapeutic intervention, resulting in increased survival. more...

Organism:: Rattus norvegicus

Type:: Expression profiling by array

Dataset:: GDS4940
Platform:: GPL1355
38 Samples

Download data: CEL

Series

Accession:: GSE13428

ID:: 200013428

Select item 49402.

Hippocampus response to acetylcholinesterase inhibitor soman: time course

Analysis of hippocampi of Sprauge-Dawley males for up to 168 hours following exposure to the acetylcholinesterase inhibitor soman. Soman is a potent neurotoxicant. Results provide insight into the molecular pathogenesis of soman-induced neurodegeneration.

Organism:: Rattus norvegicus

Type:: Expression profiling by array, transformed count, 3 agent, 10 time sets

Platform:: GPL1355
Series:: GSE13428
38 Samples

Download data: CEL

DataSet

Accession:: GDS4940

ID:: 4940

Select item 1000013553.

[Rat230_2] Affymetrix Rat Genome 230 2.0 Array

(Submitter supplied) Affymetrix submissions are typically submitted to GEO using the GEOarchive method described at http://www.ncbi.nlm.nih.gov/projects/geo/info/geo_affy.html June 03, 2009: annotation table updated with netaffx build 28 June 07, 2012: annotation table updated with netaffx build 32 June 27, 2016: annotation table updated with netaffx build 35 Protocol: see manufacturer's web site The GeneChip Rat Genome 230 2.0 Array is a powerful tool for toxicology, neurobiology, and other applications using rat as a model organism. more...