GEO DataSets

(Submitter supplied) Early mammalian development entails a series of cell fate transitions that includes transit through naïve pluripotency to post-implantation epiblast. This can subsequently give rise to primordial germ cells (PGC), the founding population of the germline lineage. To investigate the gene regulatory networks that control these critical cell fate decisions, we developed a compound-reporter system to track cellular identity in a model of PGC specification (PGC-like cells; PGCLC), and coupled it with unbiased genome-wide CRISPR screening. more...

Organism:

Mus musculus; unidentified plasmid

Type:

Expression profiling by high throughput sequencing; Other

4 related Platforms

52 Samples

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