GSM3176679[Accession] - GEO DataSets

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Items: 4

Select item 2001153701.

Progressing super-enhancer landscape during mammary differentiation controls tissue-specific gene regulation

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:: Mus musculus

Type:: Genome binding/occupancy profiling by high throughput sequencing; Expression profiling by high throughput sequencing

Platform:: GPL17021
83 Samples

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Series

Accession:: GSE115370

ID:: 200115370

PubMed Full text in PMC Similar studies

Select item 2001153682.

Progressing enhancer landscape during mammary differentiation controls gene regulation [ChIP-seq]

(Submitter supplied) The mammary luminal lineage relies on the common cytokine-sensing transcription factor STAT5 to establish super-enhancers during pregnancy and activate mammary genes required for the nutrition of the offspring. Exploiting progressive differentiation during lactation, we investigated how hormonal cues shape an evolving enhancer landscape and impact the biology of mammary cells. Employing ChIP-seq, we uncover a changing transcription factor occupancy at mammary enhancers. more...