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Items: 3

1.

Enzyme promiscuity shapes evolutionary innovation and optimization

(Submitter supplied) A computational model of underground metabolism and laboratory evolution experiments were employed to examine the role of enzyme promiscuity in the acquisition and optimization of growth on predicted non-native substrates in E. coli K-12 MG1655. After as few as 20 generations, the evolving populations repeatedly acquired the capacity to grow on five predicted novel substrates--D-lyxose, D-2-deoxyribose, D-arabinose, m-tartrate, and monomethyl succinate--none of which could support growth in wild-type cells. more...
Organism:
Escherichia coli str. K-12 substr. MG1655
Type:
Expression profiling by high throughput sequencing
Platform:
GPL18956
22 Samples
Download data: FPKM_TRACKING
Series
Accession:
GSE114358
ID:
200114358
2.

Illumina HiSeq 2500 (Escherichia coli str. K-12 substr. MG1655)

Organism:
Escherichia coli str. K-12 substr. MG1655
30 Series
530 Samples
Download data
Platform
Accession:
GPL18956
ID:
100018956
3.

D-arabionse Exp. 1 Flask 9 - Rep 2

Organism:
Escherichia coli str. K-12 substr. MG1655
Source name:
cell cultures
Platform:
GPL18956
Series:
GSE114358
Download data: FPKM_TRACKING
Sample
Accession:
GSM3140436
ID:
303140436
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db=gds|term=GSM3140436[Accession]|query=1|qty=2|blobid=MCID_674f87ea68e51b28f582be8a|ismultiple=true|min_list=5|max_list=20|def_tree=20|def_list=|def_view=|url=/Taxonomy/backend/subset.cgi?|trace_url=/stat?
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