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Items: 4

1.

Effect of Sirolimus treatment on lupus nephritis in NZB/W F1 female mice

(Submitter supplied) NZB/WF1 female mice spontaneously develop autoimmune lupus nephritis. Expression profiling of kidney tissue from (a) 12 week NZB/W F1 female mice defined as asymptomatic for lupus nephritis, (b) 36 and 42 week NZB/W F1 female mice defined as diseased/symptomatic for lupus nephritis and (c) 36 and 42 week NZB/W F1 female mice that are diseased/symptomatic for lupus nephritis and treated with Sirolimus was carried out. more...
Organism:
Mus musculus
Type:
Expression profiling by array
Dataset:
GDS4186
Platforms:
GPL76 GPL75
32 Samples
Download data: CEL
Series
Accession:
GSE12024
ID:
200012024
2.
Full record GDS4186

Lupus nephritis model response to sirolimus-induced mTOR inhibition (Mu11KsubA)

Analysis of kidney from sirolimus-treated NZB/W F1 females at 36 and 42 weeks of age. Sirolimus, a mammalian target of rapamycin (mTOR) inhibitor, has been efficacious in the NZB/W model of lupus nephritis. Results provide insight into role of the mTOR pathway in autoimmune lupus nephritis.
Organism:
Mus musculus
Type:
Expression profiling by array, count, 3 age, 2 agent, 2 disease state sets
Platform:
GPL75
Series:
GSE12024
16 Samples
Download data: CEL
3.

[Mu11KsubA] Affymetrix Murine 11K SubA Array

(Submitter supplied) Affymetrix submissions are typically submitted to GEO using the GEOarchive method described at http://www.ncbi.nlm.nih.gov/projects/geo/info/geo_affy.html June 03, 2009: annotation table updated with netaffx build 28 June 21, 2012: annotation table updated with netaffx build 32 July 08, 2016: annotation table updated with netaffx build 35 Protocol: see manufacturer's web site Has 13179 entries and was indexed 29-Jan-2002. more...
Organism:
Mus musculus
18 DataSets
29 Series
422 Samples
Download data
Platform
Accession:
GPL75
ID:
100000075
4.

SLE-7 #3 @36wks, asymptomatic on treatment with sirolimus (-2101365196)

Organism:
Mus musculus
Source name:
SLE-7 #3 @36wks
Platform:
GPL75
Series:
GSE12024
Dataset:
GDS4186
Download data: CEL
Sample
Accession:
GSM303979
ID:
300303979
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db=gds|term=GSM303979[Accession]|query=1|qty=2|blobid=MCID_674cf569f363504c2f360334|ismultiple=true|min_list=5|max_list=20|def_tree=20|def_list=|def_view=|url=/Taxonomy/backend/subset.cgi?|trace_url=/stat?
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