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Items: 4

1.

Facultative dosage compensation of developmental genes on autosomes in Drosophila and mammals

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.
Organism:
Mus musculus; Drosophila melanogaster
Type:
Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing
4 related Platforms
69 Samples
Download data: BW
Series
Accession:
GSE109901
ID:
200109901
2.

Facultative dosage compensation of developmental genes on autosomes in Drosophila and mammals [ChIP-seq Dmel]

(Submitter supplied) Haploinsufficiency and aneuploidy are two phenomena, where alteration of gene dosage causes severe cellular defects ultimately resulting in developmental failures and disease. One remarkable exception is the X chromosome, where copy number differences between males and females are buffered through the action of dosage compensation systems. In Drosophila, the Male-Specific Lethal complex (MSLc) mediates two-fold upregulation of the single male X chromosome via Histone H4 lysine 16 acetylation (H4K16ac). more...
Organism:
Drosophila melanogaster
Type:
Genome binding/occupancy profiling by high throughput sequencing
Platforms:
GPL23323 GPL19132
38 Samples
Download data: BED, BW
Series
Accession:
GSE109898
ID:
200109898
3.

Illumina HiSeq 3000 (Drosophila melanogaster)

Organism:
Drosophila melanogaster
50 Series
667 Samples
Download data
Platform
Accession:
GPL23323
ID:
100023323
4.

Dmel_male_msl2null_H3_H4K16ac_Input

Organism:
Drosophila melanogaster
Source name:
third instar larvae
Platform:
GPL23323
Series:
GSE109898 GSE109901
Download data
Sample
Accession:
GSM2973478
ID:
302973478
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