GSM2936139[Accession] - GEO DataSets

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Items: 3

Select item 2001092621.

Joint profiling of chromatin accessibility, DNA methylation and transcription in single cells

(Submitter supplied) Parallel single-cell sequencing protocols represent powerful methods for investigating regulatory relationships, including epigenome-transcriptome interactions. Here, we report the first single-cell method for parallel chromatin accessibility, DNA methylation and transcriptome profiling. scNMT-seq (single-cell nucleosome, methylation and transcription sequencing) uses a GpC methyltransferase to label open chromatin followed by bisulfite and RNA sequencing. more...

Organism:: Mus musculus; synthetic construct

Type:: Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing; Methylation profiling by high throughput sequencing