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Items: 4

1.

The molecular basis of T-PLL is an actionable perturbation of TCL1/ATM- and epigenetically instructed damage responses

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.
Organism:
Homo sapiens; Mus musculus
Type:
Expression profiling by array; Genome variation profiling by SNP array
4 related Platforms
276 Samples
Download data: CEL, CNCHP, IDAT
Series
Accession:
GSE107513
ID:
200107513
2.

The molecular basis of T-PLL is an actionable perturbation of TCL1/ATM- and epigenetically instructed damage responses [murine SNP array]

(Submitter supplied) T-cell prolymphocytic leukemia (T-PLL) is a rare and poor-prognostic mature T-cell malignancy. To address its incomplete molecular concept, we integrated large-scale profiling data of alterations in gene expression, allelic copy number (CN), and nucleotide sequences in 111 well-characterized patients. Besides prominent signatures of T-cell activation and prevalent clonal variants, we also identified novel hot-spots for CN variability, fusion molecules, alternative transcripts, and progression-associated dynamics. more...
Organism:
Mus musculus
Type:
Genome variation profiling by SNP array
Platform:
GPL13147
12 Samples
Download data: CEL, TXT
Series
Accession:
GSE107510
ID:
200107510
3.

[MOUSEDIVm520650] Affymetrix Mouse Diversity Genotyping Array

(Submitter supplied) Affymetrix submissions are typically submitted to GEO using the GEOarchive method described at http://www.ncbi.nlm.nih.gov/projects/geo/info/geo_affy.html Below table was obtained after merging the corresponding CN or SNP annot.csv files provided by Affymetrix: MOUSEDIVm520650.cn.na32.annot.csv #%create_date=2011-09-20 GMT-08:00 14:37:53 #%chip_type=MOUSEDIVm520650 #%genome-species=Mus musculus #%genome-version=mm9 #%genome-version-ucsc=mm9 #%genome-version-ncbi=37 #%genome-version-create_date=2007-07-00 #%dbSNP_date=2010-09-23 #%dbSNP_version=132 #%netaffx-annotation-date=2011-06-22 #%netaffx-annotation-netaffx-build=32 MOUSEDIVm520650.na32.annot.csv #%create_date=2011-10-24 GMT-08:00 16:10:34 #%chip_type=MOUSEDIVm520650 #%genome-species=Mus musculus #%genome-version=mm9 #%genome-version-ucsc=mm9 #%genome-version-ncbi=37 #%genome-version-create_date=2007-07-00 #%dbSNP_date=2010-09-23 #%dbSNP_version=132 #%netaffx-annotation-date=2011-06-22 #%netaffx-annotation-netaffx-build=32 Protocol: see manufacturer's web site
Organism:
Mus musculus
21 Series
395 Samples
Download data
Platform
Accession:
GPL13147
ID:
100013147
4.

Lckpr-TCL1A+/- T-cells; ‘chronic phase’ 3

Organism:
Mus musculus
Source name:
splenic isolates from T-cell leukemia / lymphoma bearing Lckpr-hTCL1A+/- mice
Platform:
GPL13147
Series:
GSE107510 GSE107513
Download data: CEL
Sample
Accession:
GSM2870356
ID:
302870356
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