GEO DataSets

(Submitter supplied) The estrogen receptor is the master transcriptional regulator of breast cancer phenotype and the archetype of a molecular therapeutic target. We mapped all estrogen receptor and RNA polymerase II binding sites on a genome-wide scale, identifying the authentic cis binding sites and target genes, in breast cancer cells. Combining this unique resource with gene expression data demonstrates distinct temporal mechanisms of estrogen-mediated gene regulation,particularly in the case of estrogen-suppressed genes. more...

Organism:

Homo sapiens

Type:

Expression profiling by array

Dataset:

GDS3285

Platform:

GPL570

12 Samples

Download data: CEL

Analysis of MCF-7 breast cancer cells treated with estrogen for up to 12 hours. Results used in conjunction with estrogen receptor and RNA polymerase II binding data to provide insight into the mechanisms underlying estrogen-regulated gene expression in breast cancer.

Organism:

Homo sapiens

Type:

Expression profiling by array, transformed count, 4 time sets

Platform:

GPL570

Series:

GSE11324

12 Samples

Download data: CEL

(Submitter supplied) Affymetrix submissions are typically submitted to GEO using the GEOarchive method described at http://www.ncbi.nlm.nih.gov/projects/geo/info/geo_affy.html June 03, 2009: annotation table updated with netaffx build 28 June 06, 2012: annotation table updated with netaffx build 32 June 23, 2016: annotation table updated with netaffx build 35 Protocol: see manufacturer's web site Complete coverage of the Human Genome U133 Set plus 6,500 additional genes for analysis of over 47,000 transcripts All probe sets represented on the GeneChip Human Genome U133 Set are identically replicated on the GeneChip Human Genome U133 Plus 2.0 Array. more...

Organism:

Homo sapiens

602 DataSets

5671 Series

61 Related Platforms

175585 Samples

Download data