GSM2796043[Accession] - GEO DataSets

Warning: The NCBI web site requires JavaScript to function. more...

Format

Summary
Summary (text)
Unique Identifier List

Sort by

Default order
Number of Samples (High to Low)
Number of Samples (Low to High)

Send to:

Choose Destination

File
Clipboard
Collections

Search results

Items: 4

Select item 2001299561.

Functional genomics of iMEF SDHC-loss stable line

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:: Mus musculus

Type:: Genome binding/occupancy profiling by high throughput sequencing; Other; Expression profiling by high throughput sequencing

Platform:: GPL21103
68 Samples

Download data: BEDGRAPH, CSV, HIC

Series

Accession:: GSE129956

ID:: 200129956

Select item 2001043622.

iMEF SDHC-loss ChIP-seq

(Submitter supplied) We have developed a tet-inducible immortalized mouse embryonic fibroblast (iMEF) cell culture system for studying the cross-talk between TCA cycle metabolism and the epigenome, in which silencing gene rearrangement of the Sdhc floxed allele is driven by doxycycline-dependent expression of cre-recombinase from a tet-inducible promoter (R26M2rtTA/+;TetOcre;Sdhcfl/fl). Using this model and an isogenic Sdhc wt control line (R26M2rtTA/+;TetOcre;Sdhcfl/wt), we have characterized differences in H3K4me3, H3K27me3, and chromatin succinylation that occur genome-wide in response to SDHC loss. more...