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Items: 4

1.

Liver Genomic Responses to Ciguatoxin (P-CTX-1)

(Submitter supplied) Ciguatoxins (CTX) are polyether neurotoxins responsible for ciguatera, the most common fish-borne food poisoning in humans. This study characterizes the global transcriptional response of mouse liver to a symptomatic dose (0.26 ng/g) of the highly potent Pacific ciguatoxin-1 (P-CTX-1). At 1 h post exposure 2.4% of features on a 44K whole genome array were differentially expressed (p ≤ 0.0001), increasing to 5.2% at 4 h and decreasing to 1.4% by 24 h post-CTX exposure. more...
Organism:
Mus musculus
Type:
Expression profiling by array
Dataset:
GDS3259
Platform:
GPL2872
9 Samples
Download data
Series
Accession:
GSE10768
ID:
200010768
2.
Full record GDS3259

Liver response to Pacific ciguatoxin-1: time course

Analysis of adult male C57/BL6 livers exposed to a symptomatic dose of the marine neurotoxin Pacific ciguatoxin-1 (P-CTX-1) for up to 24 hours. Ciguatoxins (CTX) are polyether neurotoxins that target voltage-gated sodium channels. Results provide insight into the hepatic molecular response to CTX.
Organism:
Mus musculus
Type:
Expression profiling by array, log10 ratio, 3 time sets
Platform:
GPL2872
Series:
GSE10768
9 Samples
Download data
DataSet
Accession:
GDS3259
ID:
3259
3.

Agilent-012694 Whole Mouse Genome G4122A (Feature Number version)

(Submitter supplied) Designed to truly represent all known genes in the mouse genome and their resulting transcripts, Agilent's Whole Mouse Genome Oligo microarray is comprised of 41,534 60-mer oligonucleotide probes representing over 41,000 mouse genes and transcripts. Content for this microarray was generated from leading public databases, including RefSeq, RIKEN, NIA, Ensembl, RIKEN, UCSC Goldenpath, and Unigene. Arrays of this design have barcodes that begin with 16012694 or 2512694. more...
Organism:
Mus musculus
3 DataSets
84 Series
1 Related Platform
957 Samples
Download data: TXT
Platform
Accession:
GPL2872
ID:
100002872
4.

Liver_Ciguatoxin (P-CTX-1)_1h_718+

Organism:
Mus musculus
Source name:
Liver from mice exposed to 1% Tween 60 in physiological saline (vehicle) (channel 1) Liver from mouse exposed to 0.26 ng/g Pacific Ciguatoxin-1 (channel 2)
Platform:
GPL2872
Series:
GSE10768
Dataset:
GDS3259
Download data
Sample
Accession:
GSM271869
ID:
300271869
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