GSM2706048[Accession] - GEO DataSets

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Items: 4

Select item 2001015571.

Expression of Hox transcription factors in Drosophila S2 cells

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:: Drosophila melanogaster

Type:: Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing

Platforms:: GPL13304 GPL21306
42 Samples

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Series

Accession:: GSE101557

ID:: 200101557

PubMed Full text in PMC Similar studies

Select item 2001015542.

Genomic binding profiling upon expression of AbdA in S2 cells

(Submitter supplied) We sought to determine the genomic binding profile of the Drosophila Hox protein AbdA in a homogenous cell system. S2-DRSC cells that have no Hox expression were stably transfected with HA-tagged AbdA under the control of a metallothionein promoter. Upon AbdA expression, we identified high enrichment of AbdA at a large number transcription start sites that colocalises with the GAGA and M1BP. Genes targeted by GAGA and M1BP contain paused RNA polymerase II and show enrichment of PcG proteins. more...