GSM2700518[Accession] - GEO DataSets - NCBI

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Items: 4

Select item 2001012341.

CD95L derived si- and shRNAs kill cancer cells through an RNAi mechanism by targeting survival genes [shL3.shR6.RNAseq.lg]

(Submitter supplied) The death receptor CD95/Fas can be activated by immune cells to kill cancer cells. However, most siRNAs or shRNAs targeting either CD95 or CD95L induce DICE (Death Induced by CD95/CD95L Elimination), a form of cell death in which a combination of different cell death pathways are activated, that is selective for transformed cells, and that preferentially affects cancer stem cells. We now provide evidence that both CD95 and CD95L are part of a network of genes that contain sequences that when expressed as either siRNAs or shRNAs are toxic to cancer cells. more...

Organism:: Homo sapiens

Type:: Expression profiling by high throughput sequencing

Platform:: GPL20301
16 Samples

Download data: XLSX

Series

Accession:: GSE101234

ID:: 200101234

PubMed Full text in PMC Similar studies Analyze with GEO2R SRA Run Selector

Select item 2000878172.

CD95L derived si- and shRNAs kill cancer cells through an RNAi mechanism by targeting survival genes

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:: Homo sapiens

Type:: Expression profiling by high throughput sequencing; Non-coding RNA profiling by high throughput sequencing

Platform:: GPL20301
56 Samples

Series

Accession:: GSE87817

ID:: 200087817

PubMed Full text in PMC Similar studies

Select item 1000203013.

Illumina HiSeq 4000 (Homo sapiens)

Organism:: Homo sapiens

8533 Series
195986 Samples

Platform

Accession:: GPL20301

ID:: 100020301

Select item 3027005184.

HeyA8 R6 KO C11 pLKO-R6 50hrs (duplicate 2, lg)

Organism:: Homo sapiens

Source name:: Derived from from HEY-T30 ATCC CRL-3252

Platform:: GPL20301
Series:: GSE87817 GSE101234

Sample

Accession:: GSM2700518

ID:: 302700518

SRA Run Selector

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GSM2700518[Accession] (4)
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