GSM2696874[Accession] - GEO DataSets

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Items: 4

Select item 2001009391.

Global analysis of gene expression changes following LINE1 inhibition

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:: Mus musculus

Type:: Expression profiling by high throughput sequencing

Platforms:: GPL21103 GPL17021
33 Samples

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Accession:: GSE100939

ID:: 200100939

PubMed Full text in PMC Similar studies

Select item 2001009382.

Global analysis of gene expression changes following LINE1 inhibition [II]

(Submitter supplied) Transposable elements make up nearly half of mammalian genomes, yet are generally described as ‘junk DNA’ or genome parasites. The LINE1 retrotransposon is the most abundant class and is thought to be deleterious for cells, but it is paradoxically expressed at high levels during early development. Here, we report that LINE1 plays essential roles in mouse embryonic stem (ES) cells and pre-implantation embryos. more...