GSM26690[Accession] - GEO DataSets

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Items: 4

Select item 2000015521.

gene activation by IFNs in wild type and Pias1 null BMMs

(Submitter supplied) Microarray analysis was designed to study the effect of PIAS1 on interferon (IFN) signaling pathway by comparing the gene activation profiles of wild type and Pias1 null cells in response to IFN treatments. Microarray analysis was performed essentially following the manufacturer’s instructions (Affymetrix). Briefly, bone marrow-derived macrophages (BMMs) from wile type or Pias1 null littermates were either untreated, or treated with IFN-beta (500 U/ml) or IFN-gamma (10 ng/ml) for 2h or 4h. more...

Organism:: Mus musculus

Type:: Expression profiling by array

Dataset:: GDS788
Platform:: GPL81
10 Samples

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Series

Accession:: GSE1552

ID:: 200001552

Select item 7882.

Interferon signaling in PIAS1 null mutants: time course

Expression profiling of bone marrow derived macrophages of PIAS1 null mutants treated with 500 U/ml interferon (IFN)-beta or 10 ng/ml IFN-gamma for 2 and 4 hours. IFN activates the STAT pathway, which is negatively regulated by PIAS1. Antiviral activity of IFN is enhanced in PIAS1 nulls.

Organism:: Mus musculus

Type:: Expression profiling by array, count, 3 agent, 2 genotype/variation, 3 time sets

Platform:: GPL81
Series:: GSE1552
10 Samples

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DataSet

Accession:: GDS788

ID:: 788

Select item 1000000813.

[MG_U74Av2] Affymetrix Murine Genome U74A Version 2 Array

(Submitter supplied) Affymetrix submissions are typically submitted to GEO using the GEOarchive method described at http://www.ncbi.nlm.nih.gov/projects/geo/info/geo_affy.html June 03, 2009: annotation table updated with netaffx build 28 June 07, 2012: annotation table updated with netaffx build 32 June 24, 2016: annotation table updated with netaffx build 35 Protocol: see manufacturer's web site The MG-U74 set includes 3 arrays with a total of 36899 entries and was indexed 29-Jan-2002. more...