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Items: 3

1.

MiR-34a controls proliferation and plasticity of early-progenitors in the normal mammary gland and in breast cancer

(Submitter supplied) The miR-34 is a tumor-suppressor miRNA family involved in various human cancers, including breast. However, the role of such miRNAs in the control of mammary stem cells (MaSCs), early-progenitors and their tumor counterparts, (CSCs) lies largely unexplored. Here, we identified miR-34a as directly regulated by TP53 in primary mouse mammospheres. Expression of miR-34a is induced upon luminal commitment and differentiation and able to inhibit the expansion of the MaSCs/early-progenitor pool in a p53-independent fashion. more...
Organism:
Mus musculus
Type:
Expression profiling by high throughput sequencing
Platform:
GPL13112
12 Samples
Download data: XLSX
Series
Accession:
GSE99401
ID:
200099401
2.

Illumina HiSeq 2000 (Mus musculus)

Platform
Accession:
GPL13112
ID:
100013112
3.

SCA+_NI -1

Organism:
Mus musculus
Source name:
FACS sorted Sca-1 positive cells infected with a lentiviral inducible vector expressing miR-34a; NI=not induced with doxycycline
Platform:
GPL13112
Series:
GSE99401
Download data
Sample
Accession:
GSM2643530
ID:
302643530
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db=gds|term=GSM2643530[Accession]|query=1|qty=2|blobid=MCID_675a8405532d590a6f2353d6|ismultiple=true|min_list=5|max_list=20|def_tree=20|def_list=|def_view=|url=/Taxonomy/backend/subset.cgi?|trace_url=/stat?
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