GSM2589928[Accession] - GEO DataSets

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Items: 4

Select item 2000982601.

Promoter DNA sequence guides factors that position the +1 nucleosome and facilitate TBP binding

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:: Saccharomyces cerevisiae; Saccharomyces cerevisiae S288C; Saccharomyces cerevisiae W303

Type:: Expression profiling by array; Genome binding/occupancy profiling by high throughput sequencing

Platforms:: GPL17342 GPL11232
64 Samples

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Series

Accession:: GSE98260

ID:: 200098260

Select item 2000982592.

Promoter DNA sequence guides factors that position the +1 nucleosome and facilitate TBP binding [sequencing]

(Submitter supplied) Here we present evidence that precise positioning of the +1 promoter nucleosome in yeast is critical for efficient TBP binding and pre-initiation complex assembly, and is determined, at least in part, by the action of two key factors, the essential chromatin remodeler RSC and one (or more) of a small set of ubiquitous pioneer transcription factors (PTFs). Despite their widespread co-localization, we show that RSC and PTFs often act independently to generate accessible chromatin. more...