GSM2588516[Accession] - GEO DataSets

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Items: 4

Select item 2000981441.

Differential impact of Dicer deficiency on microglia of the developing and adult brain

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:: Mus musculus

Type:: Expression profiling by high throughput sequencing; Expression profiling by array

Platforms:: GPL19057 GPL17912
52 Samples

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Series

Accession:: GSE98144

ID:: 200098144

Select item 2000981422.

Differential impact of Dicer deficiency on microglia of the developing and adult brain (Bulk RNA-Seq)

(Submitter supplied) Microglia seed the embryonic neuro-epithelium, expand and actively sculpt neuronal circuits in the developing CNS, but eventually adopt relative quiescence and ramified morphology in the adult. Here we probed the impact of post-transcriptional control by microRNAs (miRNAs) on microglial performance during development and adulthood by generating mice lacking microglial dicer expression at these distinct stages. more...