GEO DataSets

(Submitter supplied) Hereditary Hemochromatosis (HH) is an autosomal recessive disorder characterized by an abnormally low expression or functional derangement of the iron regulatory hormone hepcidin. The absorption of dietary iron is disproportionate in these patients, leading to iron deposition in several tissues and consequent damage of organs including liver, heart, and pancreas. Late complications in absence of diagnosis and treatment include cirrhosis, hepatocellular carcinoma, cardiomyopathy and diabetes. more...

Organism:

Mus musculus

Type:

Expression profiling by array

Dataset:

GDS3086

Platform:

GPL4234

12 Samples

Download data: TXT

Analysis of cardiac and skeletal muscles of animals fed a high-iron diet to induce iron overload. The cardiac muscle is a tissue affected by iron overload. Result provides insight into the molecular mechanisms underlying the pathological effect of iron overload on muscle cells.

Organism:

Mus musculus

Type:

Expression profiling by array, count, 2 protocol, 2 tissue sets

Platform:

GPL4234

Series:

GSE9726

12 Samples

Download data: TXT

(Submitter supplied) The Sentrix Mouse-6 BeadChip can be used to study expression of over 47,000 mouse transcripts based on MEEBO, RefSeq and RIKEN FANTOM2 content. researchers can generate whole-genome expression profiles for 6 samples in parallel on a single BeadChip. Each array is composed of 3 micron features with average feature redundancy of 30-fold . All features are QCed by a sequential hybridization process called array decoding. more...

Organism:

Mus musculus

4 DataSets

17 Series

303 Samples

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