GSM2323913[Accession] - GEO DataSets

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Items: 4

Select item 2000871821.

Annotation and cluster analysis of spatiotemporal- and sex-related lncRNA expression in Rhesus macaque brain

(Submitter supplied) Long noncoding RNAs (lncRNAs) mediate important epigenetic regulation in a wide range of biological processes and diseases. We applied comprehensive analyses of RNA-seq and CAGE-seq (cap analysis of gene expression and sequencing) to characterize the dynamic changes in lncRNA expression in rhesus macaque (Macaca mulatta) brain in four representative age groups. We identified 18 anatomically diverse lncRNA modules and 14 mRNA modules representing spatial, age and sex specificities. more...

Organism:: Macaca mulatta

Type:: Expression profiling by high throughput sequencing

Platforms:: GPL21120 GPL14954
128 Samples

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Accession:: GSE87182

ID:: 200087182

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Select item 2000871762.

Spatiotemporal- and sex-specific Dynamics of lncRNA expression links to brain development and aging in Rhesus Macaque (CAGE-seq)

(Submitter supplied) Dynamic remodeling in architecture and function of mammalian brain, especially in primate, rely on a precisely orchestrated molecular and cellular regulation at distinct levels. Here, we applied comprehensive RNA-seq and CAGE-Seq analysis to characterize dynamics of lncRNA expression in Rhesus macaque brain across postnatal development and aging. We identified 18 anatomically diverse lncRNA modules and 14 mRNA modules representing spatial, age and sex specificities respectively. more...