GSM216668[Accession] - GEO DataSets

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Items: 4

Select item 2000087331.

Folate deficiency enhances arsenic effects on ODC mouse skin gene expression

(Submitter supplied) We demonstrate that expression of key markers of keratinocyte differentiation is suppressed by exposure to sodium arsenite. Folate deficiency exacerbates this effect. In addition, cancer-related cell movement genes, and growth and proliferation genes are altered. Several redox-sensitive transcription factors are implicated in mediating these gene expression changes due to arsenic treatment and folate deficiency. more...

Organism:: Mus musculus

Type:: Expression profiling by array

Dataset:: GDS2872
Platform:: GPL1261
24 Samples

Download data: CEL

Series

Accession:: GSE8733

ID:: 200008733

Select item 28722.

Folate deficiency and arsenic effect on the skin

Analysis of skin from transgenic K6/ODC animals maintained on a folate deficient diet and exposed to 1 or 10 ppm sodium arsenate. K6/ODC mice develop skin tumors when exposed to sodium arsenite. Results provide insight into the combined effect of folate deficiency and arsenic on the skin.

Organism:: Mus musculus

Type:: Expression profiling by array, count, 2 agent, 3 dose, 2 protocol sets

Platform:: GPL1261
Series:: GSE8733
24 Samples

Download data: CEL

DataSet

Accession:: GDS2872

ID:: 2872

Select item 1000012613.

[Mouse430_2] Affymetrix Mouse Genome 430 2.0 Array

(Submitter supplied) Affymetrix submissions are typically submitted to GEO using the GEOarchive method described at http://www.ncbi.nlm.nih.gov/projects/geo/info/geo_affy.html June 03, 2009: annotation table updated with netaffx build 28 June 07, 2012: annotation table updated with netaffx build 32 June 23, 2016: annotation table updated with netaffx build 35 Protocol: see manufacturer's web site All probe sets represented on the GeneChip Mouse Expression Set 430 are included on the GeneChip Mouse Genome 430 2.0 Array. more...