GSM2063223[Accession] - GEO DataSets

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Items: 3

Select item 2000779751.

Genome-wide profiling of copy-number alteration in monoclonal gammopathy of undetermined significance

(Submitter supplied) Monoclonal gammopathy of undetermined significance (MGUS) is a benign condition with an approximate 1% annual risk of symptomatic plasma cell disorder development, mostly to multiple myeloma (MM). We performed genome-wide screening of copy-number alterations (CNAs) in 90 MGUS and 33 MM patients using high-density DNA microarrays. We identified CNAs in a smaller proportion of MGUS (65.6%) than in MM (100.0%, p=1.31×10-5) and showed median number of CNAs is lower in MGUS (3, range 0-22) than in MM (13, range 4-38, p=1.82×10-10). more...

Organism:: Homo sapiens

Type:: Genome variation profiling by genome tiling array; Genome variation profiling by SNP array

4 related Platforms
136 Samples

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Accession:: GSE77975

ID:: 200077975

Select item 1000113582.

Agilent-029830 Human Genome CGH + SNP Microarray (Feature Number version)

(Submitter supplied) 029830_D_20100817 ISCA plus CGH+SNP 180K Microarray Arrays of this design have barcodes that begin with 16029830 or 2529830. Orientation: Features are numbered Left-to-Right, Top-to-Bottom as scanned by an Agilent scanner (barcode on the left, DNA on the back surface, scanned through the glass), matching the FeatureNum output from Agilent's Feature Extraction software. The ID column represents the Agilent Feature Extraction feature number. more...