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Items: 4

1.

Small bowel adenocarcinoma copy number profiles are more closely related to colorectal than to gastric cancers

(Submitter supplied) Purpose: Small bowel adenocarcinoma (SBA) is a rare cancer and consequently the number of clinical trials has been very limited due to the small numbers of patients. Chemotherapy regimens are currently rather arbitrarily chosen between either a colorectal (CRC) or a gastric cancer (GC) regimen. Chromosomal copy number aberrations are a hallmark of solid tumours and can be measured by array comparative genomic hybridization (aCGH). more...
Organism:
Homo sapiens
Type:
Genome variation profiling by array; Genome variation profiling by genome tiling array
11 related Platforms
91 Samples
Download data: TXT
Series
Accession:
GSE23418
ID:
200023418
2.

Multiple genes at the chromosome 20q amplicon contribute to colorectal adenoma to carcinoma progression

(Submitter supplied) Chromosomal instability (CIN) is the hallmark of colorectal adenoma to carcinoma progression in 85% of cases, with 20q gain as the most prominent aberration. Yet, the oncogenes at this chromosomal gain are still largely unknown. Here, we aimed to identify oncogenes at 20q involved in colorectal adenoma to carcinoma progression by measuring the effect of 20q gain on gene expression in this amplicon. more...
Organism:
Homo sapiens
Type:
Expression profiling by array; Genome variation profiling by genome tiling array
5 related Platforms
217 Samples
Download data
Series
Accession:
GSE8067
ID:
200008067
3.

VUMC MACF human 5K BAC v16

(Submitter supplied) - clones were mapped to the UCSC July 2003 Freeze of the Human Golden Path (NCBI build 34) - oncobacs were mapped using their overgo-primers and are available via www.ensembl.org Protocol: as described in: Carvalho et al (J. Clin. Path.,2004, vol. 57, 644-646). DNA from the 1 Mb resolution Sanger BAC clone set (see Ensembl), the Caltech OncoBac set, and in house clones of interest, supplemented with clones from the Children’s Hospital Oakland Research Institute (CHORI), amounting to a total of 4678 clones with known chromosomal positions, was isolated according to the CHORI protocol. more...
Organism:
Homo sapiens
3 Series
91 Samples
Download data
Platform
Accession:
GPL3442
ID:
100003442
4.

Carcinoma component of a progressed adenoma (P8C_s19_b16)

Organism:
Homo sapiens
Source name:
colon (channel 1) male Reference DNA (channel 2)
Platform:
GPL3442
Series:
GSE8067 GSE23418
Download data
Sample
Accession:
GSM197888
ID:
300197888
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