GEO DataSets

(Submitter supplied) Gentamicin is a highly efficacious antibiotic against gram-negative bacteria. However, its usefulness in treating infection is compromised by its poorly understood renal toxicity. This toxic effect is seen in a variety of organisms. While the yeast Saccharomyces cerevisiae is relatively insensitive to gentamicin, mutations in any one of 20 or so genes causes a dramatic increase in sensitivity. Many of these genes encode proteins important for translation termination or specific protein trafficking complexes. more...

Organism:

Saccharomyces cerevisiae

Type:

Expression profiling by array

Dataset:

GDS2999

Platform:

GPL90

8 Samples

Download data: CEL, CHP

Analysis of Saccharomyces cerevisiae strain 4073 cultures treated with gentamicin. Gentamicin is an antibiotic used against gram-negative bacterial infections. Its usefulness is limited by nephrotoxicity. Results provide insight into the molecular mechanisms underlying gentamicin's renal toxicity.

Organism:

Saccharomyces cerevisiae

Type:

Expression profiling by array, count, 2 agent sets

Platform:

GPL90

Series:

GSE7188

8 Samples

Download data: CEL, CHP

(Submitter supplied) Affymetrix submissions are typically submitted to GEO using the GEOarchive method described at http://www.ncbi.nlm.nih.gov/projects/geo/info/geo_affy.html June 03, 2009: annotation table updated with netaffx build 28 June 08, 2012: annotation table updated with netaffx build 32 : annotation table updated with netaffx build July 01, 2016: annotation table updated with netaffx build 35 Protocol: see manufacturer's web site Has 9335 entries and was indexed 29-Jan-2002. more...

Organism:

Saccharomyces cerevisiae

52 DataSets

166 Series

2445 Samples

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