GSM170889[Accession] - GEO DataSets

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Items: 4

Select item 2000071141.

Comparative analysis of a CML cell line resistant to cyclophosphamide using oligonucleotide arrays and response to TKI

(Submitter supplied) Acquired imatinib resistance in chronic myelogenous leukemia (CML) can be the consequence of mutations in the kinase domain of BCR-ABL or increased protein levels. However, as in other malignancies, acquired resistance to cytostatic drugs is a common reason for treatment failure or disease progression. As a model for drug resistance, we developed a CML cell line resistant to cyclophosphamide (CP). Using oligonucleotide arrays, we examined changes in global gene expression. more...

Organism:: Homo sapiens

Type:: Expression profiling by array

Dataset:: GDS2729
Platform:: GPL8300
10 Samples

Download data: CEL

Series

Accession:: GSE7114

ID:: 200007114

Select item 27292.

Cyclophosphamide-resistant chronic myelogenous leukemia cell line

Analysis of chronic myelogenous leukemia (CML) cells resistant to cyclophosphamide (CP), an alkylating anticancer drug. Results provide insight into the molecular basis of CP resistance in CML.

Organism:: Homo sapiens

Type:: Expression profiling by array, count, 2 cell line sets

Platform:: GPL8300
Series:: GSE7114
10 Samples

Download data: CEL

DataSet

Accession:: GDS2729

ID:: 2729

Select item 1000083003.

[HG_U95Av2] Affymetrix Human Genome U95 Version 2 Array

(Submitter supplied) Affymetrix submissions are typically submitted to GEO using the GEOarchive method described at http://www.ncbi.nlm.nih.gov/projects/geo/info/geo_affy.html June 03, 2009: annotation table updated with netaffx build 28 June 08, 2012: annotation table updated with netaffx build 32 June 27, 2016: annotation table updated with netaffx build 35 Protocol: see manufacturer's web site Based on this UniGene build and associated annotations, the HG-U95Av2 array represents approximately 10,000 full-length genes. more...