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Items: 4

1.

Gene and microRNA expression profiling of a melanoma cell line resistant to BRAF inhibitor PLX4032 compared to the parental sensitive counterpart

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.
Organism:
Homo sapiens
Type:
Expression profiling by array; Non-coding RNA profiling by array
Platforms:
GPL20194 GPL13938
15 Samples
Download data: TXT
Series
Accession:
GSE68841
ID:
200068841
2.

Gene and microRNA expression profiling of a melanoma cell line resistant to BRAF inhibitor PLX4032 compared to the parental sensitive counterpart (miRNA)

(Submitter supplied) Gene and microRNA expression profiles were generated for a melanoma cell line resistant to the BRAF inhibitor PLX4032 and its parental cell line in order to identify altered gene-microRNA regulatory networks. Results showed that CCL2 acts as an autocrine factor and coordinately regulates, via HIF1, miR-34a, miR-100 and miR-125b, which are involved in cell proliferation and apoptosis. Inhibition of CCL2 and of the specific miRNAs restores sensitivity to BRAF inhibitors.
Organism:
Homo sapiens
Type:
Non-coding RNA profiling by array
Platform:
GPL20194
8 Samples
Download data: TXT
Series
Accession:
GSE68839
ID:
200068839
3.

Agilent-035758 Human miRBASE 16.0 plus 031181

(Submitter supplied) see manufacturer's website
Organism:
Homo sapiens
7 Series
76 Samples
Download data: TXT
Platform
Accession:
GPL20194
ID:
100020194
4.

LM16R_rep3

Organism:
Homo sapiens
Source name:
melanoma cell line derived from nodal metastasis
Platform:
GPL20194
Series:
GSE68839 GSE68841
Download data: TXT
Sample
Accession:
GSM1683176
ID:
301683176
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