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Items: 4

1.

Response of IRF7-deficient peripheral blood mononuclear cells to pH1N1 influenza virus infection

(Submitter supplied) IRF7 plays a critical role in the production and amplification of the antiviral type I and III interferon response. Autosomal recessive IRF7-deficiency resulted in life-threatening influenza disease in a 3-year-old child. We studied the impact of IRF7-deficiency in non-hematopoietic tissues (fibroblasts and lung epithelial cells) as well in hematopoietic cells (peripheral blood mononuclear cells (PBMCs)). more...
Organism:
Homo sapiens
Type:
Expression profiling by array
Dataset:
GDS5626
Platform:
GPL10558
18 Samples
Download data: TXT
Series
Accession:
GSE66486
ID:
200066486
2.
Full record GDS5626

pH1N1 influenza virus infection of interferon regulatory factor 7-deficient peripheral blood mononuclear cells: time course

Analysis of PBMCs isolated from an IRF7-deficient patient and infected with influenza A/CA/4/2009 for up to 16 hrs. Transcription factor IRF7 amplifies type I and III interferon response to viruses. Results provide insight into the role of IRF7 in antiviral immunity.
Organism:
Homo sapiens
Type:
Expression profiling by array, transformed count, 6 individual, 2 infection, 3 time sets
Platform:
GPL10558
Series:
GSE66486
18 Samples
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3.

Illumina HumanHT-12 V4.0 expression beadchip

(Submitter supplied) The HumanHT-12 v4 Expression BeadChip provides high throughput processing of 12 samples per BeadChip without the need for expensive, specialized automation. The BeadChip is designed to support flexible usage across a wide-spectrum of experiments. The updated content on the HumanHT-12 v4 Expression BeadChips provides more biologically meaningful results through genome-wide transcriptional coverage of well-characterized genes, gene candidates, and splice variants. more...
Organism:
Homo sapiens
51 DataSets
2943 Series
4 Related Platforms
104956 Samples
Download data: TXT
Platform
Accession:
GPL10558
ID:
100010558
4.

Ctrl4 FLU_16h

Organism:
Homo sapiens
Source name:
control_PBMC_FLU_16hr
Platform:
GPL10558
Series:
GSE66486
Dataset:
GDS5626
Download data
Sample
Accession:
GSM1623224
ID:
301623224
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