GSM1575301[Accession] - GEO DataSets

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Items: 4

Select item 2000645991.

The Role of Interleukin-23 in the Early Development of Emphysema in HIV1+ Smokers

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:: Homo sapiens

Type:: Expression profiling by array; Expression profiling by high throughput sequencing

Platforms:: GPL570 GPL9115
42 Samples

Download data: CEL, CHP

Series

Accession:: GSE64599

ID:: 200064599

Analyze with GEO2R

Select item 2000645982.

The Role of Interleukin-23 in the Early Development of Emphysema in HIV1+ Smokers [RNA-seq]

(Submitter supplied) Matrix metalloproteinase-9 (MMP-9) expression is up-regulated in alveolar macrophages (AM) of HIV1+ smokers who develop emphysema. Based on the knowledge that lung epithelial lining fluid (ELF) of HIV1+ smokers has increased levels of inflammatory cytokines compared to HIV1- smokers, we hypothesized up-regulation of lung cytokines in HIV1+ smokers may be functionally related to increased MMP-9 expression. more...